SMAD1 as a biomarker and potential therapeutic target in drug-resistant multiple myeloma

• Main Authors: Jian Wu (Author), Min Zhang (Author), Omar Faruq (Author), Eldad Zacksenhaus (Author), Wenming Chen (Author), Aijun Liu (Author), Hong Chang (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background SMAD1, a central mediator in TGF-β signaling, is involved in a broad range of biological activities including cell growth, apoptosis, development and immune response, and is implicated in diverse type of malignancies. Whether SMAD1 plays an important role in multiple myeloma (MM)...