Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models

Coupling biorelevant in vitro dissolution with in silico physiological-based pharmacokinetic (PBPK) tools represents a promising method to describe and predict the in vivo performance of drug candidates in formulation development including non-passive transport, prodrug activation, and first-pass me...

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Bibliographic Details
Main Authors: Alexander Denninger (Author), Tim Becker (Author), Ulrich Westedt (Author), Karl G. Wagner (Author)
Format: Book
Published: MDPI AG, 2023-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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