Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma

• Autores principales: Lukas O. Dialer (Autor), Andreas Jodal (Autor), Roger Schibli (Autor), Simon M. Ametamey (Autor), Martin Béhé (Autor)
• Formato: Libro
• Publicado: SpringerOpen, 2018-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Analogues of exendin-4 have been radiolabeled for imaging the glucagon-like peptide type 1 receptors (GLP-1R) which are overexpressed in insulinoma. The aim of this research was to synthesize an 18F-labeled silicon containing exendin-4 peptide (18F-2) and to evaluate its in vitro...