Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma

Abstract Background Analogues of exendin-4 have been radiolabeled for imaging the glucagon-like peptide type 1 receptors (GLP-1R) which are overexpressed in insulinoma. The aim of this research was to synthesize an 18F-labeled silicon containing exendin-4 peptide (18F-2) and to evaluate its in vitro...

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Main Authors: Lukas O. Dialer (Author), Andreas Jodal (Author), Roger Schibli (Author), Simon M. Ametamey (Author), Martin Béhé (Author)
Format: Book
Published: SpringerOpen, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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