Targeting Loss of Heterozygosity: A Novel Paradigm for Cancer Therapy
Loss of heterozygosity (LOH) is a common genetic event in the development of cancer. In certain tumor types, LOH can affect more than 20% of the genome, entailing loss of allelic variation in thousands of genes. This reduction of heterozygosity creates genetic differences between tumor and normal ce...
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| Main Authors: | , |
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| Format: | Book |
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MDPI AG,
2021-01-01T00:00:00Z.
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