Expanding DdCBE-mediated targeting scope to aC motif preference in rat
An animal model harboring pathogenic mitochondrial DNA (mtDNA) mutations is important to understand the biological links between mtDNA variation and mitochondrial diseases. DdCBE, a DddA-derived cytosine base editor, has been utilized in zebrafish, mice, and rats for tC sequence-context targeting an...
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Principais autores: | , , , , , , , , , , , , , , , , , , |
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Elsevier,
2023-06-01T00:00:00Z.
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A1234.567 |
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