Fabrication of Core Crosslinked Polymeric Micelles as Nanocarriers for Doxorubicin Delivery: Self-Assembly, <i>In Situ</i> Diselenide Metathesis and Redox-Responsive Drug Release

• Principais autores: Yihenew Simegniew Birhan (Autor), Haile Fentahun Darge (Autor), Endiries Yibru Hanurry (Autor), Abegaz Tizazu Andrgie (Autor), Tefera Worku Mekonnen (Autor), Hsiao-Ying Chou (Autor), Juin-Yih Lai (Autor), Hsieh-Chih Tsai (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Polymeric micelles (PMs) have been used to improve the poor aqueous solubility, slow absorption and non-selective biodistribution of chemotherapeutic agents (CAs), albeit, they suffer from disassembly and premature release of payloads in the bloodstream. To alleviate the thermodynamic instability of...