Fabrication of Core Crosslinked Polymeric Micelles as Nanocarriers for Doxorubicin Delivery: Self-Assembly, <i>In Situ</i> Diselenide Metathesis and Redox-Responsive Drug Release

• 主要な著者: Yihenew Simegniew Birhan (著者), Haile Fentahun Darge (著者), Endiries Yibru Hanurry (著者), Abegaz Tizazu Andrgie (著者), Tefera Worku Mekonnen (著者), Hsiao-Ying Chou (著者), Juin-Yih Lai (著者), Hsieh-Chih Tsai (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2020-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Polymeric micelles (PMs) have been used to improve the poor aqueous solubility, slow absorption and non-selective biodistribution of chemotherapeutic agents (CAs), albeit, they suffer from disassembly and premature release of payloads in the bloodstream. To alleviate the thermodynamic instability of...