The Regulation of Human β-Defensin 2 by the ETS Transcription Factor MEF (Myeloid Elf-1-Like Factor) Is Enhanced by Promyelocytic Leukemia Protein

• Päätekijät: Mary Ann Suico (Tekijä), Zhuo Lu (Tekijä), Tsuyoshi Shuto (Tekijä), Tomoaki Koga (Tekijä), Tomoko Uchikawa (Tekijä), Hiroki Yoshida (Tekijä), Kazuhito Matsuzaki (Tekijä), Mitsuyoshi Nakao (Tekijä), Jian-Dong Li (Tekijä), Hirofumi Kai (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2004-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The human β-defensin 2 (HBD 2) is a potent anti-bacterial peptide with a wide spectrum of activity. MEF (myeloid elf-1-like factor) or Elf4, a member of the ETS transcription factor family, has been shown to up-regulate the basal expression of the HBD 2 gene in epithelial cells. The mammalian cell n...