Phytochemical study and pharmacological activity of Terminalia chebula fruit extracts activity as Dihydrofolate Reductase enzyme inhibitors associated with antioxidant effect: In vitro study

• Главные авторы: Marwah Mohammed Salih Ali (Автор), Mayssaa Essam Abdalah (Автор), Bahir Abdul-Razzaq Mshimesh (Автор)
• Формат: ‌
• Опубликовано: College of Pharmacy / Mustansiriyah University, 2023-01-01T00:00:00Z.
• Предметы: article
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Dihydrofolate reductase (DHFR) is a fundamental enzyme in producing the precursor of purines and pyrimidines for biosynthesis of DNA, RNA and amino acids at various stages. It is considered the key target for both anticancer and antimicrobial drug design. Terminalia chebula has unique phytoconstitue...