Phytochemical study and pharmacological activity of Terminalia chebula fruit extracts activity as Dihydrofolate Reductase enzyme inhibitors associated with antioxidant effect: In vitro study

• Ngā kaituhi matua: Marwah Mohammed Salih Ali (Author), Mayssaa Essam Abdalah (Author), Bahir Abdul-Razzaq Mshimesh (Author)
• Hōputu: Pukapuka
• I whakaputaina: College of Pharmacy / Mustansiriyah University, 2023-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Dihydrofolate reductase (DHFR) is a fundamental enzyme in producing the precursor of purines and pyrimidines for biosynthesis of DNA, RNA and amino acids at various stages. It is considered the key target for both anticancer and antimicrobial drug design. Terminalia chebula has unique phytoconstitue...