The Effectiveness of Imipenem-Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase

The Effectiveness of Imipenem-Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase

Background: Ceftazidime-avibactam was approved by the FDA to treat infections caused by Enterobacterales carrying <i>bla</i><sub>KPC-2</sub>. However, variants of KPC-2 with amino acid substitutions at position 179 have emerged and confer resistance to ceftazidime-avibactam....

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Main Authors: Krisztina M. Papp-Wallace (Author), Melissa D. Barnes (Author), Magdalena A. Taracila (Author), Christopher R. Bethel (Author), Joseph D. Rutter (Author), Elise T. Zeiser (Author), Katherine Young (Author), Robert A. Bonomo (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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