The Effectiveness of Imipenem-Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase

• Asıl Yazarlar: Krisztina M. Papp-Wallace (Yazar), Melissa D. Barnes (Yazar), Magdalena A. Taracila (Yazar), Christopher R. Bethel (Yazar), Joseph D. Rutter (Yazar), Elise T. Zeiser (Yazar), Katherine Young (Yazar), Robert A. Bonomo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Ceftazidime-avibactam was approved by the FDA to treat infections caused by Enterobacterales carrying <i>bla</i>_KPC-2. However, variants of KPC-2 with amino acid substitutions at position 179 have emerged and confer resistance to ceftazidime-avibactam....