Cover Image

Monitoring Tacrolimus Concentrations in Whole Blood and Peripheral Blood Mononuclear Cells: Inter- and Intra-Patient Variability in a Cohort of Pediatric Patients

Tacrolimus (TAC) is a first-choice immunosuppressant for solid organ transplantation, characterized by high potential for drug-drug interactions, significant inter- and intra-patient variability, and narrow therapeutic index. Therapeutic drug monitoring (TDM) of TAC concentrations in whole blood (WB...

Full description

Saved in:

Bibliographic Details
Main Authors:	Amedeo De Nicolò (Author), Michele Pinon (Author), Alice Palermiti (Author), Antonello Nonnato (Author), Alessandra Manca (Author), Jacopo Mula (Author), Silvia Catalano (Author), Francesco Tandoi (Author), Renato Romagnoli (Author), Antonio D'Avolio (Author), Pier Luigi Calvo (Author)
Format:	Book
Published:	Frontiers Media S.A., 2021-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Stability Study of Fosfomycin in Elastomeric Pumps at 4 °C and 34 °C: Technical Bases for a Continuous Infusion Use for Outpatient Parenteral Antibiotic Therapy
by: Alessandra Manca, et al.
Published: (2023)

Monitoring Intra-cellular Tacrolimus Concentrations in Solid Organ Transplantation: Use of Peripheral Blood Mononuclear Cells and Graft Biopsy Tissue
by: Benedetta C. Sallustio, et al.
Published: (2021)

Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV
by: Amedeo De Nicolò, et al.
Published: (2020)

Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants
by: Jessica Cusato, et al.
Published: (2022)

A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues
by: Alessandra Manca, et al.
Published: (2023)

Apoptosis of peripheral blood mononuclear cells in patients with sepsis
by: Jadali Zohreh, et al.
Published: (2010)

Clinical Effectiveness and Pharmacokinetics of Dalbavancin in Treatment-Experienced Patients with Skin, Osteoarticular, or Vascular Infections
by: Giacomo Stroffolini, et al.
Published: (2022)

Factors Influencing the Intracellular Concentrations of the Sofosbuvir Metabolite GS-331007 (in PBMCs) at 30 Days of Therapy
by: Jessica Cusato, et al.
Published: (2022)

Human Endogenous Retroviruses Are Preferentially Expressed in Mononuclear Cells From Cord Blood Than From Maternal Blood and in the Fetal Part of Placenta
by: Massimiliano Bergallo, et al.
Published: (2020)

NBAS mutations cause acute liver failure: when acetaminophen is not a culprit
by: Pier Luigi Calvo, et al.
Published: (2017)

Cytotoxic Effect of Recombinant Fragaceatoxin C on Peripheral Blood Mononuclear Cells
by: Leyla Darbarfard, et al.
Published: (2020)

Aldosterone Synthesis and Cytokine Production in Human Peripheral Blood Mononuclear Cells
by: Ryuzea Miura, et al.
Published: (2006)

Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children
by: Chiara Lanzillotta, et al.
Published: (2020)

Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells
by: Miura Ryuzea, et al.
Published: (2006)

Evaluation of cytokines in peripheral blood mononuclear cell supernatants for the diagnosis of tuberculosis
by: Sariko M, et al.
Published: (2018)

A Non-Invasive Method for Detection of Antihypertensive Drugs in Biological Fluids: The Salivary Therapeutic Drug Monitoring
by: Valeria Avataneo, et al.
Published: (2022)

COVID-19: Focusing on the Link between Inflammation, Vitamin D, MAPK Pathway and Oxidative Stress Genetics
by: Jessica Cusato, et al.
Published: (2023)

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.
by: Nisha Jain Garg, et al.
Published: (2016)

Pharmacokinetic of Cefiderocol in Critically Ill Patients Receiving Renal Replacement Therapy: A Case Series
by: Simone Mornese Pinna, et al.
Published: (2022)

Whole Transcriptome Analysis (RNA Sequencing) of Peripheral Blood Mononuclear Cells of Vitiligo Patients
by: E. Reimann, et al.
Published: (2014)

Virucidal potential of Prosopis spicigera and Mangifera indica on human peripheral blood mononuclear cells
by: Amit Gupta, et al.
Published: (2016)

Mitochondrial and Redox Changes in Periodontitis and Type 2 Diabetes Human Blood Mononuclear Cells
by: Ildete L. Ferreira, et al.
Published: (2023)

The identification of circular RNAs from peripheral blood mononuclear cells in systemic lupus erythematosus
by: Fengping Zheng, et al.
Published: (2021)

CYTOTOXIC AND ANTI-VIRAL ACTIVITY OF Acacia catechu ON HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS
by: Amit Gupta, et al.
Published: (2016)

Expression profile of circRNA in peripheral blood mononuclear cells of patients with rheumatoid arthritis
by: Huangxin Lu, et al.
Published: (2022)

Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells
by: Junying Lu, et al.
Published: (2018)

Development and Validation of an Up-to-Date Highly Sensitive UHPLC-MS/MS Method for the Simultaneous Quantification of Current Anti-HIV Nucleoside Analogues in Human Plasma
by: Amedeo De Nicolò, et al.
Published: (2021)

Effect of Blood Component Coatings of Enosseal Implants on Proliferation and Synthetic Activity of Human Osteoblasts and Cytokine Production of Peripheral Blood Mononuclear Cells
by: Lucie Himmlova, et al.
Published: (2016)

Cytotoxic activity of peripheral blood mononuclear cells in patients with endometriosis: A cross-sectional study
by: Raden Muharam, et al.
Published: (2022)

Nafamostat Mesilate Induces Production of Interleukin-12 and -18 in Human Peripheral Blood Mononuclear Cells
by: Goutarou Katsuno, et al.
Published: (2005)

Cardiotrophin-1 Induces Tumor Necrosis Factor Synthesis in Human Peripheral Blood Mononuclear Cells
by: Michael Fritzenwanger, et al.
Published: (2009)

CRP and TNF-α Induce PAPP-A Expression in Human Peripheral Blood Mononuclear Cells
by: Weiping Li, et al.
Published: (2012)

Analysis of Cannabinoids Concentration in Cannabis Oil Galenic Preparations: Harmonization between Three Laboratories in Northern Italy
by: Alice Palermiti, et al.
Published: (2021)

Paracrine Factors of Stressed Peripheral Blood Mononuclear Cells Activate Proangiogenic and Anti-Proteolytic Processes in Whole Blood Cells and Protect the Endothelial Barrier
by: Dragan Copic, et al.
Published: (2022)

HEALING OF DIABETIC FOOT ULCER USING AUTOLOGOUS PERIPHERAL BLOOD MONONUCLEAR STEM CELLS (STUDY CASE)
by: Basuki Supartono, -
Published: (2018)

Response of peripheral blood mononuclear cells to conditioned medium from cultured oral squamous cell carcinomas
by: Cristiane Miranda França, et al.
Published: (2011)

Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production
by: Longo Dan L, et al.
Published: (2011)

The Effect of Paracrine Factors Released by Irradiated Peripheral Blood Mononuclear Cells on Neutrophil Extracellular Trap Formation
by: Katharina Klas, et al.
Published: (2022)

Apoptosis in Peripheral Blood Mononuclear Cells of Chemical Victims 25 Years after Exposure to Mustard Gas
by: Alamdar L., et al.
Published: (2015)

Differential gene expression in peripheral blood mononuclear cells from children immunized with inactivated influenza vaccine
by: John F. Alcorn, et al.
Published: (2020)