1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein

• मुख्य लेखकों: Yang Liu (लेखक), Kuiru Sa (लेखक), Wei Xu (लेखक), Yongkang Chen (लेखक), Jing Liang (लेखक), Peng Zou (लेखक), Lixia Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Compuscript Ltd, 2023-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2. Here, we established a method to screen inhibitors of N protein by using microscale thermophoresis assays to obtain potentia...