Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine

• Hauptverfasser: Stefano Vitello (Verfasst von), Italia Di Liegro (Verfasst von), Maria Rita Ricciardi (Verfasst von), Chiara Verga (Verfasst von), Alessandra Amato (Verfasst von), Gabriella Schiera (Verfasst von), Carlo Di Liegro (Verfasst von), Giuseppe Messina (Verfasst von), Patrizia Proia (Verfasst von)
• Format: Buch
• Veröffentlicht: PAGEPress Publications, 2020-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Tumorigenesis is a multiphasic process in which genetic alterations guide the progressive transformation in cancer cells1. In order to evaluate the possible correlation between some gene variants and the risk of the toxicity development onset, two of the polymorphisms of the thymidylate synthase (TY...