Calcium and Reactive Oxygen Species Mediated Zn2+-Induced Apoptosis in PC12 Cells

• Asıl Yazarlar: Shinji Abe (Yazar), Hideki Ohnishi (Yazar), Koichiro Tsuchiya (Yazar), Keisuke Ishizawa (Yazar), Mayumi Torii (Yazar), Yasuhisa Kanematsu (Yazar), Kazuyoshi Kawazoe (Yazar), Kazuo Minakuchi (Yazar), Masanori Yoshizumi (Yazar), Toshiaki Tamaki (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2006-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The release of excessive Zn2+ from presynaptic boutons into extracellular regions contributes to neuronal apoptotic events, which result in neuronal cell death. However, the mechanisms of Zn2+-induced neuronal cell death are still unclear. Therefore, we investigated the dynamics of intracellular Zn2...