Pharmacokinetic/Pharmacodynamic Analysis and Dose Optimization of Cefmetazole and Flomoxef against Extended-Spectrum β-Lactamase-Producing <i>Enterobacterales</i> in Patients with Invasive Urinary Tract Infection Considering Renal Function

• Autori principali: Yukihiro Hamada (Autore), Hidefumi Kasai (Autore), Moeko Suzuki-Ito (Autore), Yasufumi Matsumura (Autore), Yohei Doi (Autore), Kayoko Hayakawa (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The optimal regimens of cefmetazole and flomoxef for the treatment of urinary tract infections caused by extended-spectrum β-lactamase (ESBL)-producing <i>Enterobacterales</i> are not well defined. Our study found that the pharmacokinetic/pharmacodynamic targets for cefmetazole and flomo...