Roles and inhibitors of FAK in cancer: current advances and future directions
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that exhibits high expression in various tumors and is associated with a poor prognosis. FAK activation promotes tumor growth, invasion, metastasis, and angiogenesis via both kinase-dependent and kinase-independent pathways. Moreover, FAK...
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Frontiers Media S.A.,
2024-02-01T00:00:00Z.
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