Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages

• Главные авторы: Etta Y.L. Liu (Автор), Yingjie Xia (Автор), Xiangpeng Kong (Автор), Maggie S.S. Guo (Автор), Anna X.D. Yu (Автор), Brody Z.Y. Zheng (Автор), Shinghung Mak (Автор), Miranda L. Xu (Автор), Karl W.K. Tsim (Автор)
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• Опубликовано: Elsevier, 2020-10-01T00:00:00Z.
• Предметы: article
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Acetylcholine (ACh) regulates inflammation via α7 nicotinic acetylcholine receptor (α7 nAChR). Acetylcholinesterase (AChE), an enzyme hydrolyzing ACh, is expressed in immune cells suggesting non-classical function in inflammatory responses. Here, the expression of PRiMA-linked G4 AChE was identified...