Setting up a new gold standard: automated temperature-controlled hERG test on Patchliner®

In the present study, the Patchliner® temperature-controlled automated patch clamp system was evaluated for testing actions of drugs on K+ currents through hERG channels expressed in CHO cells at 35-37°C. Obtained IC50 values for a set of reference drugs were matched with those obtained using conven...

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Bibliographic Details
Main Author: Liudmila ePolonchuk (Author)
Format: Book
Published: Frontiers Media S.A., 2012-01-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available