Setting up a new gold standard: automated temperature-controlled hERG test on Patchliner®
In the present study, the Patchliner® temperature-controlled automated patch clamp system was evaluated for testing actions of drugs on K+ currents through hERG channels expressed in CHO cells at 35-37°C. Obtained IC50 values for a set of reference drugs were matched with those obtained using conven...
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| 格式: | 圖書 |
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Frontiers Media S.A.,
2012-01-01T00:00:00Z.
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| 索引號: |
A1234.567 |
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