Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice

• Автори: John R. Counsell (Автор), Rajvinder Karda (Автор), Juan Antinao Diaz (Автор), Louise Carey (Автор), Tatiana Wiktorowicz (Автор), Suzanne M.K. Buckley (Автор), Shima Ameri (Автор), Joanne Ng (Автор), Julien Baruteau (Автор), Filipa Almeida (Автор), Rohan de Silva (Автор), Roberto Simone (Автор), Eleonora Lugarà (Автор), Gabriele Lignani (Автор), Dirk Lindemann (Автор), Axel Rethwilm (Автор), Ahad A. Rahim (Автор), Simon N. Waddington (Автор), Steven J. Howe (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2018-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Viral vectors are rapidly being developed for a range of applications in research and gene therapy. Prototype foamy virus (PFV) vectors have been described for gene therapy, although their use has mainly been restricted to ex vivo stem cell modification. Here we report direct in vivo transgene deliv...