Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

• Main Authors: Armstrong Stephen R (Author), Narendrula Rashmi (Author), Guo Baoqing (Author), Parissenti Amadeo M (Author), McCallum Katherine L (Author), Cull Stephanie (Author), Lannér Carita (Author)
• Format: Book
• Published: BMC, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not unc...