Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

• Autori principali: Armstrong Stephen R (Autore), Narendrula Rashmi (Autore), Guo Baoqing (Autore), Parissenti Amadeo M (Autore), McCallum Katherine L (Autore), Cull Stephanie (Autore), Lannér Carita (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2012-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not unc...