Nicorandil inhibits cardiomyocyte apoptosis and improves cardiac function by suppressing the HtrA2/XIAP/PARP signaling after coronary microembolization in rats

• Autori principali: Jing Zheng (Autore), Manyun Long (Autore), Zhenbai Qin (Autore), Fen Wang (Autore), Zhiqing Chen (Autore), Lang Li (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2021-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Cardiomyocyte apoptosis is a key factor in the deterioration of cardiac function after coronary microembolization (CME). Nicorandil (NIC) affects myocardial injury, which may be related to the inhibition of apoptosis. However, the specific mechanism of cardioprotection has not been elucidat...