Nicorandil inhibits cardiomyocyte apoptosis and improves cardiac function by suppressing the HtrA2/XIAP/PARP signaling after coronary microembolization in rats

• मुख्य लेखकों: Jing Zheng (लेखक), Manyun Long (लेखक), Zhenbai Qin (लेखक), Fen Wang (लेखक), Zhiqing Chen (लेखक), Lang Li (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Cardiomyocyte apoptosis is a key factor in the deterioration of cardiac function after coronary microembolization (CME). Nicorandil (NIC) affects myocardial injury, which may be related to the inhibition of apoptosis. However, the specific mechanism of cardioprotection has not been elucidat...