High occurrence of <it>BRCA1 </it>intragenic rearrangements in hereditary breast and ovarian cancer syndrome in the Czech Republic

• Päätekijät: Kuklova Jitka (Tekijä), Pavlu Hana (Tekijä), Horky Ondrej (Tekijä), Damborsky Jiri (Tekijä), Lukesova Miroslava (Tekijä), Machackova Eva (Tekijä), Vasickova Petra (Tekijä), Kosinova Veronika (Tekijä), Navratilova Marie (Tekijä), Foretova Lenka (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2007-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Alterations in the highly penetrant cancer susceptibility gene <it>BRCA1 </it>are responsible for the majority of hereditary breast and/or ovarian cancers. However, the number of detected germline mutations has been lower...