Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites.

• প্রধান লেখক: Pedro Jimenez-Sandoval (Author), Eduardo Castro-Torres (Author), Rogelio González-González (Author), Corina Díaz-Quezada (Author), Misraim Gurrola (Author), Laura D Camacho-Manriquez (Author), Lucia Leyva-Navarro (Author), Luis G Brieba (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Triosephosphate isomerases (TPIs) from Taenia solium (TsTPI) and Schistosoma mansoni (SmTPI) are potential vaccine and drug targets against cysticercosis and schistosomiasis, respectively. This is due to the dependence of parasitic helminths on glycolysis and because those proteins elicit an immune...