Microencapsulated Chitosan-Based Nanocapsules: A New Platform for Pulmonary Gene Delivery

In this work, we propose chitosan (CS)-based nanocapsules (NCs) for pulmonary gene delivery. Hyaluronic acid (HA) was incorporated in the NCs composition (HA/CS NCs) aiming to promote gene transfection in the lung epithelium. NCs were loaded with a model plasmid (pCMV-βGal) to easily evaluate their...

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Main Authors: Estefanía Fernández-Paz (Author), Lucía Feijoo-Siota (Author), Maria Manuela Gaspar (Author), Noemi Csaba (Author), Carmen Remuñán-López (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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