Chromone hybrids as interleukin-6 and acetylcholinesterase inhibitor for treatment of Alzheimer's disease: Design, docking, synthesis and evaluation

• Ngā kaituhi matua: Shivam Mishra (Author), Sukhvir Kaur (Author), Gulshan Bansal (Author), Yogita Bansal (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2024-12-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The course of Alzheimer's disease (AD) is largely influenced by interleukin-6 (IL-6) and acetylcholinesterase (AChE). Therefore, concurrent suppression of these two targets is a rational approach for the development of anti-AD molecules. The study is aimed to design a molecule with pharmacophor...