Chromone hybrids as interleukin-6 and acetylcholinesterase inhibitor for treatment of Alzheimer's disease: Design, docking, synthesis and evaluation

• Những tác giả chính: Shivam Mishra (Tác giả), Sukhvir Kaur (Tác giả), Gulshan Bansal (Tác giả), Yogita Bansal (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2024-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The course of Alzheimer's disease (AD) is largely influenced by interleukin-6 (IL-6) and acetylcholinesterase (AChE). Therefore, concurrent suppression of these two targets is a rational approach for the development of anti-AD molecules. The study is aimed to design a molecule with pharmacophor...