An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.

• मुख्य लेखकों: Meghan A Guzman (लेखक), Anastasia R Rugel (लेखक), Reid S Tarpley (लेखक), Sevan N Alwan (लेखक), Frédéric D Chevalier (लेखक), Dmytro P Kovalskyy (लेखक), Xiaohang Cao (लेखक), Stephen P Holloway (लेखक), Timothy J C Anderson (लेखक), Alexander B Taylor (लेखक), Stanton F McHardy (लेखक), Philip T LoVerde (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Currently there is only one method of treatment for human schistosomiasis, the drug praziquantel. Strong selective pressure has caused a serious concern for a rise in resistance to praziquantel leading to the necessity for additional pharmaceuticals, with a distinctly different mechanism of action,...