The Fab portion of immunoglobulin G has sites in the CL domain that interact with Fc gamma receptor IIIa

• मुख्य लेखकों: Yuki Yamaguchi (लेखक), Natsumi Wakaizumi (लेखक), Mine Irisa (लेखक), Takahiro Maruno (लेखक), Mari Shimada (लेखक), Koya Shintani (लेखक), Haruka Nishiumi (लेखक), Rina Yogo (लेखक), Saeko Yanaka (लेखक), Daisuke Higo (लेखक), Tetsuo Torisu (लेखक), Koichi Kato (लेखक), Susumu Uchiyama (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The interaction between IgG and Fc gamma receptor IIIa (FcγRIIIa) is essential for mediating immune responses. Recent studies have shown that the antigen binding fragment (Fab) and Fc are involved in IgG-FcγRIII interactions. Here, we conducted bio-layer interferometry (BLI) and isothermal titration...