Exploring BSEP Inhibition-Mediated Toxicity with a Mechanistic Model of Drug-Induced Liver Injury
Inhibition of the bile salt export pump (BSEP) has been linked to incidence of drug-induced liver injury (DILI), presumably by the accumulation of toxic bile acids in the liver. We have previously constructed and validated a model of bile acid disposition within DILIsym®, a mechanistic model of DILI...
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Materyal Türü: | Kitap |
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Frontiers Media S.A.,
2014-11-01T00:00:00Z.
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A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |