Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation

• Principais autores: Felicity Y. Han (Autor), Andrew K. Whittaker (Autor), Steven M. Howdle (Autor), Andrew Naylor (Autor), Anjumn Shabir-Ahmed (Autor), Cheng Zhang (Autor), Maree T. Smith (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2018-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Pain is inadequately relieved by escalating doses of a strong opioid analgesic such as morphine in up to 25% of patients with cancer-related severe pain complicated by a neuropathic (nerve damage) component. Hence, there is an unmet medical need for research on novel painkiller strategies. In the pr...