Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients-A Controlled Clinical Trial

• मुख्य लेखकों: Philipp Simon (लेखक), David Petroff (लेखक), David Busse (लेखक), Jana Heyne (लेखक), Felix Girrbach (लेखक), Arne Dietrich (लेखक), Alexander Kratzer (लेखक), Markus Zeitlinger (लेखक), Charlotte Kloft (लेखक), Frieder Kees (लेखक), Hermann Wrigge (लेखक), Christoph Dorn (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: This controlled clinical study aimed to investigate the impact of obesity on plasma and tissue pharmacokinetics of meropenem. Methods: Obese (body mass index (BMI) ≥ 35 kg/m²) and age-/sex-matched nonobese (18.5 kg/m² ≥ BMI ≤ 30 kg/m<sup&g...