Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients-A Controlled Clinical Trial

• প্রধান লেখক: Philipp Simon (লেখক), David Petroff (লেখক), David Busse (লেখক), Jana Heyne (লেখক), Felix Girrbach (লেখক), Arne Dietrich (লেখক), Alexander Kratzer (লেখক), Markus Zeitlinger (লেখক), Charlotte Kloft (লেখক), Frieder Kees (লেখক), Hermann Wrigge (লেখক), Christoph Dorn (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2020-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: This controlled clinical study aimed to investigate the impact of obesity on plasma and tissue pharmacokinetics of meropenem. Methods: Obese (body mass index (BMI) ≥ 35 kg/m²) and age-/sex-matched nonobese (18.5 kg/m² ≥ BMI ≤ 30 kg/m<sup&g...