MECOM and the PRDM gene family in uterine endometrial cancer: bioinformatics and experimental insights into pathogenesis and therapeutic potentials

• Main Authors: Meng Lou (Author), Lian Zou (Author), Liying Zhang (Author), Yongquan Lu (Author), Jia Chen (Author), Beige Zong (Author)
• פורמט: ספר
• יצא לאור: BMC, 2024-10-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract To elucidate the expression profiles, methylation states, and clinicopathological significance of the PRDM gene family, focusing on the MECOM gene's role in uterine endometrial cancer (UCEC) and its molecular interactions with the TGF-beta signaling pathway. Our methodology combined de...