MECOM and the PRDM gene family in uterine endometrial cancer: bioinformatics and experimental insights into pathogenesis and therapeutic potentials

• मुख्य लेखकों: Meng Lou (लेखक), Lian Zou (लेखक), Liying Zhang (लेखक), Yongquan Lu (लेखक), Jia Chen (लेखक), Beige Zong (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract To elucidate the expression profiles, methylation states, and clinicopathological significance of the PRDM gene family, focusing on the MECOM gene's role in uterine endometrial cancer (UCEC) and its molecular interactions with the TGF-beta signaling pathway. Our methodology combined de...