High EVI1 and PARP1 expression as favourable prognostic markers in high-grade serous ovarian carcinoma

• मुख्य लेखकों: Paul Jank (लेखक), Jonas Leichsenring (लेखक), Svenja Kolb (लेखक), Inga Hoffmann (लेखक), Philip Bischoff (लेखक), Catarina Alisa Kunze (लेखक), Mihnea P. Dragomir (लेखक), Moritz Gleitsmann (लेखक), Moritz Jesinghaus (लेखक), Wolfgang D. Schmitt (लेखक), Hagen Kulbe (लेखक), Christine Sers (लेखक), Albrecht Stenzinger (लेखक), Jalid Sehouli (लेखक), Ioana Elena Braicu (लेखक), Christina Westhoff (लेखक), David Horst (लेखक), Carsten Denkert (लेखक), Stefan Gröschel (लेखक), Eliane T. Taube (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2023-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are upregulated in cancers with DNA repair deficiencies with DNA repair deficiencies and may influce disease progression and surviva...