Deciphering the mechanism of Indirubin and its derivatives in the inhibition of Imatinib resistance using a "drug target prediction-gene microarray analysis-protein network construction" strategy

• Hoofdauteurs: Huayao Li (Auteur), Lijuan Liu (Auteur), Jing Zhuang (Auteur), Cun Liu (Auteur), Chao Zhou (Auteur), Jing Yang (Auteur), Chundi Gao (Auteur), Gongxi Liu (Auteur), Changgang Sun (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2019-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background The introduction of imatinib revolutionized the treatment of chronic myeloid leukaemia (CML), substantially extending patient survival. However, imatinib resistance is currently a clinical problem for CML. It is very importantto find a strategy to inhibit imatinib resistance. Met...