The influence of OATP2B1 and atorvastatin on coproporphyrin isomers in rats
Coproporphyrin I (CPI) and III (CPIII) are discussed as biomarkers for organic anion transporting polypeptides (OATPs). We report on CPI and CPIII levels in wildtype, rSlco2b1-knockout, and SLCO2B1-humanized rats at baseline and after administration of atorvastatin, an inhibitor of the CPIII-specifi...
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Elsevier,
2023-11-01T00:00:00Z.
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A1234.567 |
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