Engineered Mutation of Some Important Amino Acids in Angiotensin II Type 1 (AT1) Receptor Increases the Binding Affinity of AT1-Receptor Antagonists
The present study was designed to examine the binding affinity and functional potency of selective angiotensin II type 1 (AT1)-receptor antagonists towards specific mutants of AT1 receptor using site-directed mutagenesis. We also compared our results with the wild-type AT1 receptor and investigated...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2010-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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