Effects of triclabendazole and its metabolite exposure on the heart‐rate-corrected QT intervals: A randomized, placebo‐ and positive‐controlled thorough QT study in healthy individuals

Abstract Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of therapeutic (10 mg/kg twice daily [b.i.d.] for 1 day) and su...

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Main Authors: William T. Prince (Author), Vinay Kumar Venishetty (Author), Jean Lecot (Author), Kasra Shakeri‐Nejad (Author), Cathy Gray (Author), Amanda Taylor (Author), Ganesh R. Iyer (Author), Julia Zack (Author)
Format: Book
Published: Wiley, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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