Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

• मुख्य लेखकों: Zulfan Zazuli (लेखक), Susanne Vijverberg (लेखक), Elise Slob (लेखक), Geoffrey Liu (लेखक), Bruce Carleton (लेखक), Joris Veltman (लेखक), Paul Baas (लेखक), Rosalinde Masereeuw (लेखक), Anke-Hilse Ma (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Nephrotoxicity is a notable adverse effect in cisplatin treated patients characterized by tubular injury and/or increased serum creatinine (SCr) with incidence varying from 20 to 70%. Pharmacogenomics has been shown to identify strongly predictive genetic markers to help determine which...