The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136

• Egile Nagusiak: Fabiola Garcia Cortizo (Egilea), Daniel Pfaff (Egilea), Angela Wirth (Egilea), Andrea Schlotterer (Egilea), Rebekka Medert (Egilea), Jakob Morgenstern (Egilea), Tobias Weber (Egilea), Hans-Peter Hammes (Egilea), Thomas Fleming (Egilea), Peter Paul Nawroth (Egilea), Marc Freichel (Egilea), Aurelio A. Teleman (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Methylglyoxal (MG) is a highly reactive α-oxoaldehyde that glycates proteins. MG has been linked to the development of diabetic complications: MG is the major precursor of advanced glycation end products (AGEs), a risk marker for diabetic complications in humans. Furthermore, flies and fi...