UTP - Gated Signaling Pathways of 5-HT Release from BON Cells as a Model of Human Enterochromaffin Cells

• Autores principales: Andromeda Liñán-Rico (Autor), Fernando Ochoa-Cortes (Autor), Alix Zuleta-Alarcon (Autor), Mazin Alhaj (Autor), Esmerina Tili (Autor), Josh Enneking (Autor), Alan Harzman (Autor), Iveta Grants (Autor), Sergio Bergese (Autor), Fievos L. Christofi (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background: Enterochromaffin cells (EC) synthesize and release 5-HT and ATP to trigger or modulate gut neural reflexes and transmit information about visceral/pain sensation. Alterations in 5-HT signaling mechanisms may contribute to the pathogenesis of IBD or IBS, but the pharmacologic or molecular...