Mitochondrial H<sub>2</sub>O<sub>2</sub> Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury
Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences, including hepatic injury. The detrimental hepatotoxicity of diclofenac, a widely used NSAID, is primarily connected to oxidative damage in mitochondria, which are the primary source of reactive oxygen species (R...
Saved in:
Main Authors: | Sin Ri Kim (Author), Ji Won Park (Author), You-Jin Choi (Author), Seong Keun Sonn (Author), Goo Taeg Oh (Author), Byung-Hoon Lee (Author), Tong-Shin Chang (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Maturation of Mitochondrially Targeted Prx V Involves a Second Cleavage by Mitochondrial Intermediate Peptidase That Is Sensitive to Inhibition by H<sub>2</sub>O<sub>2</sub>
by: Juhyun Sim, et al.
Published: (2021) -
Comparative Pharmacokinetics of Gentamicin C<sub>1</sub>, C<sub>1a</sub> and C<sub>2</sub> in Healthy and Infected Piglets
by: Eun-Young Kim, et al.
Published: (2024) -
The Short Lipopeptides (C<sub>10</sub>)<sub>2</sub>-KKKK-NH<sub>2</sub> and (C<sub>12</sub>)<sub>2</sub>-KKKK-NH<sub>2</sub> Protect HaCaT Keratinocytes from Bacterial Damage Caused by <i>Staphylococcus aureus</i> Infection in a Co-Culture Model
by: Kirsten Reddersen, et al.
Published: (2020) -
H<sub>2</sub>O<sub>2</sub>/Ca<sup>2+</sup>/Zn<sup>2+</sup> Complex Can Be Considered a "Collaborative Sensor" of the Mitochondrial Capacity?
by: Ester Sara Di Filippo, et al.
Published: (2022) -
The Cytoprotective Effects of Baicalein on H<sub>2</sub>O<sub>2</sub>-Induced ROS by Maintaining Mitochondrial Homeostasis and Cellular Tight Junction in HaCaT Keratinocytes
by: Gyeonghyeon Kim, et al.
Published: (2023)