Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

• প্রধান লেখক: David Dahlgren (লেখক), Maria-Jos (লেখক), Tobias Olander (লেখক), Mikael Hedeland (লেখক), Markus Sjöblom (লেখক), Hans Lennernäs (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2020-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This model can determine intestinal permeability ba...