Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

• मुख्य लेखकों: David Dahlgren (लेखक), Maria-Jos (लेखक), Tobias Olander (लेखक), Mikael Hedeland (लेखक), Markus Sjöblom (लेखक), Hans Lennernäs (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This model can determine intestinal permeability ba...