Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This model can determine intestinal permeability ba...
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MDPI AG,
2020-03-01T00:00:00Z.
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